The article predicts the results of retrospective evaluation from 2008 to 2010. 98 mothers with genital and extragenital diseases, who had preterm infants with very low birth weight (BMI) and extremely low birth weight (BMI). Premature births directly reflect the health status of a pregnant woman. The main causes of premature births, is an infection, severe somatic condition of the mother, complications of pregnancy. The study involved 98 patients, and statistical analysis is made basic findings of the operation. The presence of psychological stress during pregnancy in mothers of children with very low body weight and extremely low body weight has been revealed. Data on the somatic status of mothers are given.