The knowledge hub of all profession is based in the field of scientific enquiry. The Nursing research has an incredible influence on the professional growth of Nursing. The reflection of nursing profession is based on the improvement in the nursing practice. Successful implementation of the research findings or evidence is essential for enhancement of present and upcoming proficient nursing practice. Nurses are facing challenges while implementing these valuable research findings into practice. There are many barriers in implementation of the research findings. Implementation of existing research findings has the key to provide best quality and excellent nursing care. The objective of this review was to explore the challenges and barriers faced by the nursing fraternity while implementing the existing research findings in to practice.