Insecurity in Nigeria has assumed a weird situation to the extent that no region of the country is immune from the nauseating experience that has led to the death of hundreds of thousands of people. For instance, a total of 1,486 people in the country were victims of insecurity in January 2022 – 915 of whom were killed and 571 were kidnapped. The south east which hitherto was a peaceful zone has turned to a theatre of killings occasioned by the intolerable activities of the unknown gunmen who take delight in the forceful sit-at home that has turned the south east into a fearful zone devoid of free movement of people. This by all intent and purposes have truncated the laudable think home philosophy of the Igbos. The dramatic surge in the activities of the unknown gunmen was as a result of the separatist agitation associated with the designation of the Indigenous People of Biafra as a terrorist organization by the Federal Government. This study will be guided by three objectives of the study among which is to examine the extent to which insecurity has affected business investments in the south east. A qualitative descriptive research design will be adopted; it is recommended that the governors of the south east should establish a security network that can fight the insecurity in the south east otherwise the region will continue to depreciate in terms of business investment.