Sheet-fed litho is commonly used for printing of short-run magazines, brochures, letter headings, and general commercial (jobbing) printing. In sheet-fed offset, "the printing is carried out on single sheets of paper as they are fed to the press one at a time". Sheet-fed presses use mechanical registration to relate each sheet to one another to ensure that they are reproduced with the same imagery in the same position on every sheet running through the press. Different types of printing substrates we can use in sheet-fed offset printing for production. Coated, Un-coated & Polypropylene (PP) substrates are considered during our research work. Aim of this study is to reduce the consumption and influence of printing substrates with the optimum utilization of printing substrates and explore the possible ways of optimum consumption of the printing substrates used in different sheet offset presses for different type of jobs. In this different type of printing substrates is study which are used in printing industries, different jobs of the “Akriti Printer” Noida” were taken into consideration. During project work jobs consuming moderate type of printing substrates were selected and the study was conducted on each selected job.