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ZENODO
Article . 2023
License: CC BY
Data sources: ZENODO
ZENODO
Article . 2023
License: CC BY
Data sources: Datacite
ZENODO
Article . 2023
License: CC BY
Data sources: Datacite
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Assessing Diagnostic Utility of NLR to Predict Poor Functional Outcomes in Patients with Hemorrhagic Stroke and To Compare it with the Intracranial Hemorrhage (ICH) Score: A Comparative Study

Authors: Arun Kumar; Nishant Kumar Singh;

Assessing Diagnostic Utility of NLR to Predict Poor Functional Outcomes in Patients with Hemorrhagic Stroke and To Compare it with the Intracranial Hemorrhage (ICH) Score: A Comparative Study

Abstract

AbstractAim: The aim of this study was to evaluate the diagnostic utility of NLR to predict poor functional outcomes inpatients with hemorrhagic stroke and to compare it with the intracranial hemorrhage (ICH) score.Material & Methods: Patients who presented to the emergency department with clinical features suggestive ofstroke were evaluated with computed tomography (CT) brain to identify ICH. The ICH scores and NLR wereestimated at the time of admission. Modified Rankin Scale (mRS) score equal to or greater than 3 at 90 days wasused to define poor functional outcomes (major disability or death). Receiver operating characteristic (ROC)curve was plotted with NLR and the ICH score to analyze and compare their discriminative ability to predictpoor functional outcomes.Results: A total of 100 patients were included in this study, 65 males and 35 females. The mean age of the studygroup was 64.6 years (SD = 12.6). 32% had ICH score 2 followed by 21% had ICH score 1. Of the total 100patients, 65 subjects (65%) had mRS score greater than or equal to 3 at 90 days. These patients were categorizedas the poor functional outcome group. 35 patients (35%) had mRS score less than 3 at 90 days and werecategorized as the good outcome group. The all-cause mortality at 90 days was 16 (16%) in the study. Thedifference of Laboratory variables and the ICH score according to 90 days of outcomes were found to bestatistically significant. At their cutoff values, NLR compared to the ICH score was found to be more sensitivebut less specific. There was no significant difference in accuracy between NLR and the ICH score.Conclusion: In patients with hemorrhagic stroke, NLR at admission is a good predictor of functional outcomesat 90 days. When compared to the ICH score, NLR is more sensitive but less specific in predicting poorfunctional outcomes.

AbstractAim: The aim of this study was to evaluate the diagnostic utility of NLR to predict poor functional outcomes inpatients with hemorrhagic stroke and to compare it with the intracranial hemorrhage (ICH) score.Material & Methods: Patients who presented to the emergency department with clinical features suggestive ofstroke were evaluated with computed tomography (CT) brain to identify ICH. The ICH scores and NLR wereestimated at the time of admission. Modified Rankin Scale (mRS) score equal to or greater than 3 at 90 days wasused to define poor functional outcomes (major disability or death). Receiver operating characteristic (ROC)curve was plotted with NLR and the ICH score to analyze and compare their discriminative ability to predictpoor functional outcomes.Results: A total of 100 patients were included in this study, 65 males and 35 females. The mean age of the studygroup was 64.6 years (SD = 12.6). 32% had ICH score 2 followed by 21% had ICH score 1. Of the total 100patients, 65 subjects (65%) had mRS score greater than or equal to 3 at 90 days. These patients were categorizedas the poor functional outcome group. 35 patients (35%) had mRS score less than 3 at 90 days and werecategorized as the good outcome group. The all-cause mortality at 90 days was 16 (16%) in the study. Thedifference of Laboratory variables and the ICH score according to 90 days of outcomes were found to bestatistically significant. At their cutoff values, NLR compared to the ICH score was found to be more sensitivebut less specific. There was no significant difference in accuracy between NLR and the ICH score.Conclusion: In patients with hemorrhagic stroke, NLR at admission is a good predictor of functional outcomesat 90 days. When compared to the ICH score, NLR is more sensitive but less specific in predicting poorfunctional outcomes.

Keywords

Functional outcomes, Hemorrhagic stroke, Intracranial hemorrhage, Modified Rankin scale, Neutrophil-to-lymphocyte ratio, The ICH score.

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
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