Introduction: Spinal anaesthesia is reliable and safe technique for perianal surgeries. 2-Chloroprocaine has a rapid onset and short duration of action and less systemic toxicity. The primary goal of ambulatory anaesthesia is rapid recovery leading to early patient discharge with minimal side effects. Aim: This study was aimed to evaluate the effectiveness of 2-chloroprocaine with or without fentanyl in perianal surgeries in terms of block characteristics as primary objective and to note haemodynamics and any side effects as secondary objective. Study design: A prospective, randomized, double blind interventional study. Methods: Sixty adult patients of 18-60 years, of either sex, ASA grade I or II posted for perianal surgeries under spinal anaesthesia were randomized into two groups of 30 each, in which one group (CF) received1% 2-chloroprocaine 3 ml (30mg) with fentanyl 0.5ml (25mcg) and other group (CS) received 1% 2-chloroprocaine 3ml (30mg) with normal saline 0.5ml. Results: The mean time to peak sensory level in Group CF was 8.20±0.96 min and in Group CS, it was 8.66±0.95 min (P = 0.065). The mean duration of sensory block in Group CF was 96.20±10.30 min and in Group CS, it was 90.60±10.92 min (P = 0.045). The mean duration of motor block in Group CF was 90.47±8.67 min and in Group CS, it was 88.43±8.67 min (P= 0.31). The mean duration of analgesia in Group CF was 117.60±11.54 min and in Group CS, it was 111.28±11.66 min (P = 0.039). Conclusion: Addition of fentanyl 25 mcg as an adjuvant to 2-chloroprocaine (30 mg) resulted in marginal but statistically significant prolongation of sensory block duration and time to rescue analgesia in patient undergoing perianal surgery under spinal anaesthesia.

Introduction: Spinal anaesthesia is reliable and safe technique for perianal surgeries. 2-Chloroprocaine has a rapid onset and short duration of action and less systemic toxicity. The primary goal of ambulatory anaesthesia is rapid recovery leading to early patient discharge with minimal side effects. Aim: This study was aimed to evaluate the effectiveness of 2-chloroprocaine with or without fentanyl in perianal surgeries in terms of block characteristics as primary objective and to note haemodynamics and any side effects as secondary objective. Study design: A prospective, randomized, double blind interventional study. Methods: Sixty adult patients of 18-60 years, of either sex, ASA grade I or II posted for perianal surgeries under spinal anaesthesia were randomized into two groups of 30 each, in which one group (CF) received1% 2-chloroprocaine 3 ml (30mg) with fentanyl 0.5ml (25mcg) and other group (CS) received 1% 2-chloroprocaine 3ml (30mg) with normal saline 0.5ml. Results: The mean time to peak sensory level in Group CF was 8.20±0.96 min and in Group CS, it was 8.66±0.95 min (P = 0.065). The mean duration of sensory block in Group CF was 96.20±10.30 min and in Group CS, it was 90.60±10.92 min (P = 0.045). The mean duration of motor block in Group CF was 90.47±8.67 min and in Group CS, it was 88.43±8.67 min (P= 0.31). The mean duration of analgesia in Group CF was 117.60±11.54 min and in Group CS, it was 111.28±11.66 min (P = 0.039). Conclusion: Addition of fentanyl 25 mcg as an adjuvant to 2-chloroprocaine (30 mg) resulted in marginal but statistically significant prolongation of sensory block duration and time to rescue analgesia in patient undergoing perianal surgery under spinal anaesthesia.