AbstractAim: The aim of the present study was to determine the importance of oesophago-gastroscopy in the diagnosticsof laryngopharyngeal reflux (LPR) induced pathology.Methods: The present study was conducted in the Department of Gastroenterology, A total of 50 patients (30women, 20 men) with laryngopharyngeal problems in whom GERD was suspected were included in the study.They were 17 −/78 years old, with a mean of 45 years and a standard deviation of 14.6 years.Results: The VHI results showed that patients with vocal fold polyps assessed their voice problems as beingworse in comparison to the voice problems of the LPR patients, but the significant difference appeared only in thephysical subtest of VHI. The subjective VHI test performed in the LPR patients after the treatment showed asignificant improvement in the overall results and in the results of all the subtests in comparison to the results ofthe test performed before the treatment. The acoustic analysis of the voice samples detected almost no change inF0 and JIT and a statistically significant improvement in SH and NHR. On the basis of videoendolaryngoscopy,the lesions of the laryngeal mucosa were evaluated using the BRFS before and after the treatment withesomeprasol. In all the LPR patients the BRFS was more than 7 before the treatment, indicating LPR. After thetreatment, the BRFS significantly decreased.Conclusion: LPR can cause serious voice disorders, globus pharyngeus sensation, or frequent coughing. Thevoice problems can be compared to the problems of patients with vocal fold polyps. Oesophago-gastroscopysupplemented with a biopsy of the oesophageal mucosa can be a suitable method to prove the occurrence of GER.Videoendolaryngoscopy and the BRFS are superior in the diagnostics of LPR and correlate very well with thehistological findings of the oesophageal mucosa specimens. The combination of all three procedures is supposedto be a very successful method in the diagnostics of GERD and especially LPR. Esomeprasol proved to be veryeffective in the treatment of LPR. 

AbstractAim: The aim of the present study was to determine the importance of oesophago-gastroscopy in the diagnosticsof laryngopharyngeal reflux (LPR) induced pathology.Methods: The present study was conducted in the Department of Gastroenterology, A total of 50 patients (30women, 20 men) with laryngopharyngeal problems in whom GERD was suspected were included in the study.They were 17 −/78 years old, with a mean of 45 years and a standard deviation of 14.6 years.Results: The VHI results showed that patients with vocal fold polyps assessed their voice problems as beingworse in comparison to the voice problems of the LPR patients, but the significant difference appeared only in thephysical subtest of VHI. The subjective VHI test performed in the LPR patients after the treatment showed asignificant improvement in the overall results and in the results of all the subtests in comparison to the results ofthe test performed before the treatment. The acoustic analysis of the voice samples detected almost no change inF0 and JIT and a statistically significant improvement in SH and NHR. On the basis of videoendolaryngoscopy,the lesions of the laryngeal mucosa were evaluated using the BRFS before and after the treatment withesomeprasol. In all the LPR patients the BRFS was more than 7 before the treatment, indicating LPR. After thetreatment, the BRFS significantly decreased.Conclusion: LPR can cause serious voice disorders, globus pharyngeus sensation, or frequent coughing. Thevoice problems can be compared to the problems of patients with vocal fold polyps. Oesophago-gastroscopysupplemented with a biopsy of the oesophageal mucosa can be a suitable method to prove the occurrence of GER.Videoendolaryngoscopy and the BRFS are superior in the diagnostics of LPR and correlate very well with thehistological findings of the oesophageal mucosa specimens. The combination of all three procedures is supposedto be a very successful method in the diagnostics of GERD and especially LPR. Esomeprasol proved to be veryeffective in the treatment of LPR.