This paper emphasizes on existing solid waste management practices in Indapur municipal area of Pune district of Maharashtra state, India. Exponential growth of population and in round development of society and industries are responsible for increased solid waste generation in city. Whereas uncontrollable and mismanaged solid waste cause adverse environmental impacts on public health and are basis of other socio-economic problems too. For reducing the expenditure on Solid Waste Management (SWM), route optimization for collection of solid waste is major component. The objective of this paper is to give a better alternative for solid waste disposal management system by route optimization using Geographical Information System for the city. This could help not only to the competent responsible authorities in municipal solid waste management but also the researchers in this field to enhance the efficient planning and strategies in this field.