
Background: In the developing world, acute organophosphorus (OP) pesticide poisoning is common. Since the nation is mostly an agricultural one, pesticides and insecticides are widely employed in agriculture, and the general public has easy access to these hazardous chemicals. The objective of the study was to identify the nature of the demographic profile, type of compound, clinical manifestations, and outcome of organophosphate poisoning presenting to a tertiary care hospital in Muzaffarpur, Bihar. Methods: Between June 2023 and November 2023, a cross-sectional study including 100 patients diagnosed with OPC poisoning at Sri Krishna Medical College and Hospital Muzaffarpur, Bihar, was carried out in the general medicine department. The diagnosis of OP poisoning was established on the basis of the patient’s medical history or any evidence of exposure to the OP chemical within a 24-hour period. Symptoms such as fasciculations, miosis, excessive salivation, and improved signs and symptoms after atropine treatment were noted. IBM SPSS version 22 was used for statistical analysis. Results: Eighty percent of the subjects were male. The bulk (66%) belonged to the 21–40 year old age range. Methyl parathion was the most often ingested OPC (27%) and was followed by chlorpyrifos (22%). Abdominal pain/cramps accounted for 100% of the significant GIT problems, with nausea and vomiting coming in second with 83%. In 40% of the individuals, mechanical ventilation was required, and 25% of the subjects had reported death. Conclusion: Males in their economically productive stages of life are disproportionately affected by OP poisoning. Given the high death rate, it is imperative that health services be adequately strengthened, particularly at the primary level.
Background: In the developing world, acute organophosphorus (OP) pesticide poisoning is common. Since the nation is mostly an agricultural one, pesticides and insecticides are widely employed in agriculture, and the general public has easy access to these hazardous chemicals. The objective of the study was to identify the nature of the demographic profile, type of compound, clinical manifestations, and outcome of organophosphate poisoning presenting to a tertiary care hospital in Muzaffarpur, Bihar. Methods: Between June 2023 and November 2023, a cross-sectional study including 100 patients diagnosed with OPC poisoning at Sri Krishna Medical College and Hospital Muzaffarpur, Bihar, was carried out in the general medicine department. The diagnosis of OP poisoning was established on the basis of the patient’s medical history or any evidence of exposure to the OP chemical within a 24-hour period. Symptoms such as fasciculations, miosis, excessive salivation, and improved signs and symptoms after atropine treatment were noted. IBM SPSS version 22 was used for statistical analysis. Results: Eighty percent of the subjects were male. The bulk (66%) belonged to the 21–40 year old age range. Methyl parathion was the most often ingested OPC (27%) and was followed by chlorpyrifos (22%). Abdominal pain/cramps accounted for 100% of the significant GIT problems, with nausea and vomiting coming in second with 83%. In 40% of the individuals, mechanical ventilation was required, and 25% of the subjects had reported death. Conclusion: Males in their economically productive stages of life are disproportionately affected by OP poisoning. Given the high death rate, it is imperative that health services be adequately strengthened, particularly at the primary level.
Organophosphorus, Pesticides, Muscarinic Manifestations, Nicotinic Manifestations, Poisoning
Organophosphorus, Pesticides, Muscarinic Manifestations, Nicotinic Manifestations, Poisoning
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