Plant based crude drugs is an important traditional medicinal practice which still using today throughout the world. Based on the different characteristics of the medicinal plantlets their therapeutic usage. Evaluation process depends on scientifically determine the qualitative microscopy. This study have greater importance for the authentication and phytochemical identification. So that their microscopical constituents have vital role for the safe utilization .The wild source plants like Annona squamosa Linn. leaf continues to draw wide attention for their role in treating diseases like Cardiac ailments, Thyroid-related disorders, Diabetes, and Cancer..etc. Present work focus on quantitative parameters of leaf transfer section and their evaluation studies like Stomatal number, Stomatal Index, Vein Islet number Vein Terminal number and Palisade ratio are reported for the future prospects to increase the standardization of these parameters for the safe utilization of crude drugs are discussed. Keywords: Annona squamosa, Traditional Medicinal plants, Phytochemicals,