Background: Circumcision is one of the oldest and most frequently performed surgical procedures done on males by pediatric surgeons. Pain management is one of the challenging tasks for both pediatric surgeons and anesthesiologists involved during the procedure of male circumcision. The aim of the present study is to systematically review the researchers conducted on pain management in pediatric male circumcision published during the past ten years. Methods: This systematic review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guideline. The literature search encompassed an extensive database including PubMed, MEDLINE, Science Direct and Embase. Studies published after the year 2012 were included in the analysis. The quality of included studies was assessed using appropriate tools tailored to the study design. The synthesis and analysis of data included a narrative summary of study characteristics, analgesic methods, pain scale used, surgical technique, and main study results. Results: Sample sizes in the selected studies ranged from 40 to over 1300 participants. Dorsal Penile Nerve Block (DPNB) was the most commonly performed regional anesthetic technique for male circumcision. Plastibell technique was the most commonly performed surgical procedures in the study. Neonatal Infant Pain Scale (NIPS) was the most commonly used pain scale in the present findings. Conclusion: In summary, the management of pain during and after male circumcision in the pediatric population has seen remarkable progress, reflecting a commitment to delivering safe, effective, and pain-free care to new-borns and infants.

Background: Circumcision is one of the oldest and most frequently performed surgical procedures done on males by pediatric surgeons. Pain management is one of the challenging tasks for both pediatric surgeons and anesthesiologists involved during the procedure of male circumcision. The aim of the present study is to systematically review the researchers conducted on pain management in pediatric male circumcision published during the past ten years. Methods: This systematic review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guideline. The literature search encompassed an extensive database including PubMed, MEDLINE, Science Direct and Embase. Studies published after the year 2012 were included in the analysis. The quality of included studies was assessed using appropriate tools tailored to the study design. The synthesis and analysis of data included a narrative summary of study characteristics, analgesic methods, pain scale used, surgical technique, and main study results. Results: Sample sizes in the selected studies ranged from 40 to over 1300 participants. Dorsal Penile Nerve Block (DPNB) was the most commonly performed regional anesthetic technique for male circumcision. Plastibell technique was the most commonly performed surgical procedures in the study. Neonatal Infant Pain Scale (NIPS) was the most commonly used pain scale in the present findings. Conclusion: In summary, the management of pain during and after male circumcision in the pediatric population has seen remarkable progress, reflecting a commitment to delivering safe, effective, and pain-free care to new-borns and infants.