Technical notes and documentation The Compendium of Healthcare Costs in Spain (CONCEPT-COSTS Database) is a database of Spanish healthcare unit costs estimated from different national sources. Version 3.0 of the CONCEPT-COSTS Database contains costs estimates (expresed in EUR 2024) for a core set of service items commonly used in the chronic health problems evaluated in CONCEPT Project. It is a living document planned to be regularly updated and expanded in terms of the covered service over time. Aims of CONCEPT-COSTS project: CONCEPT-COSTS is part of the coordinated CONCEPT Project, which comprises four subprojects whose objective is to analyse the effectiveness and efficiency of care pathways (CP) in three chronic health problems of high prevalence and socioeconomic impact, which are diabetes mellitus type 2, breast cancer and ischemic stroke. As a common denominator, CONCEPT shares the innovative perspective of focusing its analysis on CP as a key determinant of healthcare adequacy, adherence to treatment, health outcomes and economic consequences. CONCEPT-COSTS' first objective is to complement the results produced by each CONCEPT clinical cohort, with a broad proposal of economic analyses based on real-world data (RWD), including incurred costs, avoidable costs and efficiency evaluation of identified CP. These results will be used to inform the clinical and management decisions about those CP to be promoted or avoided. As a second objective, CONCEPT-COSTS will identify the ethodological and logistical challenges faced by economic evaluations based on RWD, to develop a framework that will include recommendations for improvements related to feasibility, validity and transferability of results. Files included in this publication: CONCEPT_COSTS_Database_v3.csv CONCEPT_COSTS_Database_v3.html Readme_v3.doc What's new Costs updated to 2024 Some sources updated

CONCEPT-COSTS (PI19/00306) has been financed by the Instituto de Salud Carlos III (ISCIIII); (Spain) within the Health Research and Development Strategy (AES), and belongs to the CONCEPT project. CONCEPT project is a coordinated project led by the CONCEPT-STROKE (PI19/00154). It was also financed by REDISSEC, grant Reference: RD16/0001/0014. It is now integrated within the initiatives supported by the Health Outcomes-Oriented Cooperative Research Networks (RICORS) on Research Networks in Chronicity, Primary Care, and Health Promotion (RICAPPS). Grant Reference: RD21/0016/0016. Funding Entity: Instituto de Salud Carlos III (ISCIIII); Call 2021 of the Strategic Action in Health 2017-2020, charged to the European funds of the Recovery, Transformation and Resilience Plan.