Background: Induction of labour is a commonly performed obstetrical procedure for which numerous methods are adapted and intracervical dinoprostone and intravaginal misoprostol are the most frequently used techniques. This study aimed to compare the safety and efficacy intravaginal misoprostol tablet and intracervical dinoprostone gel for induction of labour at term. Methods: The present study was conducted in a tertiary care hospital in New Delhi among pregnant females with singleton pregnancy at term requiring induction of labour for various indications. The study subjects were enrolled in group A (misoprostol group) were administered 25 mcg of misoprostol every 4th hourly to a maximum of 5 doses and in group B (dinoprostone) study subjects were administered 0.5 mg of dinoprostone every 6th hourly to a maximum of 4 doses. Results: A total of 50 cases were enrolled in both the study groups. The baseline parameters among both the study groups were comparable. Nearly two-third of study subjects in misoprostol group delivered within first 12 hours and only 12% had delivered in first 12 hours in dinoprostone group. Requirement of oxytocin augmentation of labour was nearly similar in both the study with 18% of cases in misoprostol group and 16% cases in dinoprostone group requiring it. Conclusion: Low dose vaginal misoprostol is associated with a lower incidence of uterine tachysystole and a lower caesarean delivery rate.

Background: Induction of labour is a commonly performed obstetrical procedure for which numerous methods are adapted and intracervical dinoprostone and intravaginal misoprostol are the most frequently used techniques. This study aimed to compare the safety and efficacy intravaginal misoprostol tablet and intracervical dinoprostone gel for induction of labour at term. Methods: The present study was conducted in a tertiary care hospital in New Delhi among pregnant females with singleton pregnancy at term requiring induction of labour for various indications. The study subjects were enrolled in group A (misoprostol group) were administered 25 mcg of misoprostol every 4th hourly to a maximum of 5 doses and in group B (dinoprostone) study subjects were administered 0.5 mg of dinoprostone every 6th hourly to a maximum of 4 doses. Results: A total of 50 cases were enrolled in both the study groups. The baseline parameters among both the study groups were comparable. Nearly two-third of study subjects in misoprostol group delivered within first 12 hours and only 12% had delivered in first 12 hours in dinoprostone group. Requirement of oxytocin augmentation of labour was nearly similar in both the study with 18% of cases in misoprostol group and 16% cases in dinoprostone group requiring it. Conclusion: Low dose vaginal misoprostol is associated with a lower incidence of uterine tachysystole and a lower caesarean delivery rate.