Background: The mechanism of depression and anxiety in COPD is still not completely understood. The biological mechanism between COPD and mental illness has to be evaluated. Method: 95 patients aged between 40-70 years with COPD in depression and anxiety was studied. They were subjected to a detailed clinical examination, and COPD was diagnosed as per GOLD guide lines with a post-bronchodilator fEv1/FEV<70 nMRC score. Spirometric study, psychological assessment by the HAM-D method, and anxiety assessment by the MADRS method. Results: 44 (46.3%) had anxiety, and 51 (53.6%) had depression. In a comparative study of no depression, respiratory and psychiatric parameters had a highly significant p value (p<0.001). Conclusion: COPD patients with co-morbid anxiety and repression experience more acute exacerbations and need pulmonary rehabilitation. Management of anxiety and depression in COPD will reduce readmissions and mortality.

Background: The mechanism of depression and anxiety in COPD is still not completely understood. The biological mechanism between COPD and mental illness has to be evaluated. Method: 95 patients aged between 40-70 years with COPD in depression and anxiety was studied. They were subjected to a detailed clinical examination, and COPD was diagnosed as per GOLD guide lines with a post-bronchodilator fEv1/FEV<70 nMRC score. Spirometric study, psychological assessment by the HAM-D method, and anxiety assessment by the MADRS method. Results: 44 (46.3%) had anxiety, and 51 (53.6%) had depression. In a comparative study of no depression, respiratory and psychiatric parameters had a highly significant p value (p<0.001). Conclusion: COPD patients with co-morbid anxiety and repression experience more acute exacerbations and need pulmonary rehabilitation. Management of anxiety and depression in COPD will reduce readmissions and mortality.