Background: Type 2 diabetes (T2D) is a prevalent metabolic disorder correlated with an elevated risk of cardiovascular (CV) and peripheral arterial disease (PAD). Early recognition of these conditions is essential for effective management and prevention of complications. The ankle–brachial index (ABI) has been broadly used to assess PAD; however, the significance of high ABI values in patients with T2D remains unclear. The study aimed to examine the relationship between high ABI values and the presence of CV and PAD in patients with T2D. Methods: Medical information of 200 patients with T2D who underwent ABI measurements between 2021 and 2023 were retrospectively investigated. Participants were categorized into two categories based on their ABI values: normal (0.9-1.3) and high (>1.3). The prevalence of cardiovascular events and PAD in both categories was assessed, and multivariate logistic regression measure to ascertain the independent determinants of these results. Results: Among the patients analyzed, 30 (15%) had high ABI values (>1.3). Patients with high ABI values had a significantly elevated risk of cardiovascular events (OR 2.45, 95% CI 1.75-3.43, p < 0.001) and PAD (OR 2.83, 95% CI 2.04-3.94, p < 0.001) compared to those with normal ABI values. High ABI remained an independent predictor of cardiovascular events and PAD. Conclusion: The study suggests that a high ABI is a strong indicator of CV and PAD in individuals with T2D. Physicians should consider this non-invasive and easily obtainable measurement when assessing the vascular health of these patients. Early identification of high ABI values may help improve risk stratification and guide appropriate interventions to reduce the burden of cardiovascular and peripheral arterial disease in this high-risk population. Recommendation: Consider measuring ABI in patients with Type 2 diabetes for early identification of cardiovascular and peripheral arterial disease risk.

Background: Type 2 diabetes (T2D) is a prevalent metabolic disorder correlated with an elevated risk of cardiovascular (CV) and peripheral arterial disease (PAD). Early recognition of these conditions is essential for effective management and prevention of complications. The ankle–brachial index (ABI) has been broadly used to assess PAD; however, the significance of high ABI values in patients with T2D remains unclear. The study aimed to examine the relationship between high ABI values and the presence of CV and PAD in patients with T2D. Methods: Medical information of 200 patients with T2D who underwent ABI measurements between 2021 and 2023 were retrospectively investigated. Participants were categorized into two categories based on their ABI values: normal (0.9-1.3) and high (>1.3). The prevalence of cardiovascular events and PAD in both categories was assessed, and multivariate logistic regression measure to ascertain the independent determinants of these results. Results: Among the patients analyzed, 30 (15%) had high ABI values (>1.3). Patients with high ABI values had a significantly elevated risk of cardiovascular events (OR 2.45, 95% CI 1.75-3.43, p < 0.001) and PAD (OR 2.83, 95% CI 2.04-3.94, p < 0.001) compared to those with normal ABI values. High ABI remained an independent predictor of cardiovascular events and PAD. Conclusion: The study suggests that a high ABI is a strong indicator of CV and PAD in individuals with T2D. Physicians should consider this non-invasive and easily obtainable measurement when assessing the vascular health of these patients. Early identification of high ABI values may help improve risk stratification and guide appropriate interventions to reduce the burden of cardiovascular and peripheral arterial disease in this high-risk population. Recommendation: Consider measuring ABI in patients with Type 2 diabetes for early identification of cardiovascular and peripheral arterial disease risk.