Abstract Silver nanoparticles (AA-AgNPs) were made from Albizia amara leaf extract using green synthesis. The nano-particles were characterized by X-ray diffraction spectroscopy to identify the crystalline/amorphous nature). According to the XRD pattern, the (111), (200), (220), and (222) planes have Bragg's diffraction peaks at 38.05°, 44.17°, 64.44°, and 77.32°, respectively. The face-centered cubic lattice structure of nanoparticles is thus connected to these angles. The antimicrobial activity of Albizia amara AgNPs by Disc diffusion assay. Staphylococcus aureus, or E. Coli, was discovered to be between 50 and 350 g/ml. Escherichia coli, one of these strains, was shown to be the most susceptible with a MIC value of 120 g/ml whereas Staphylococcus aureus, another strain, was discovered to be very resistant to AA AgNPs with a MIC value of 140 g/ml.