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ZENODO
Article . 2023
License: CC BY
Data sources: ZENODO
ZENODO
Article . 2023
License: CC BY
Data sources: Datacite
ZENODO
Article . 2023
License: CC BY
Data sources: Datacite
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Prospective Validation of Neutrophil-to-Lymphocyte Ratio as a Diagnostic and Management Adjunct in Acute Appendicitis

Authors: Meha Ghodawat; Kartikey Shukla; Manoj Kela; Priyal Jain;

Prospective Validation of Neutrophil-to-Lymphocyte Ratio as a Diagnostic and Management Adjunct in Acute Appendicitis

Abstract

Background: Acute appendicitis (AA) is one of the most common abdominal emergencies worldwide. Patients presenting with appendicitis may vary in severity. We conducted this study aiming top prospectively examine the role of NLR in assessing the severity of appendicitis, length of hospital stay, and rate of postoperative complications. We have 3 objectives namely to study neutrophil and lymphocyte count in appendicitis cases, to study various correlation and association regarding severity of appendicitis and neutrophil to lymphocyte ratio (NLR) & to study the validity of neutrophil to lymphocyte ratio (NLR) in predicting the severity, length of hospital stay and 30 day complication rate. The study was conducted in the department of general surgery at SAMC & PGI Indore (M.P.) from January 2018 to June 2019 on 100 patients which were selected according to inclusion and exclusion criteria Receiver Operating Characteristic (ROC) curve analysis was used for determining optimal cut-off value of NLR for complicated AA. Most of the patients with AA were in the age group of 20-29years with M:F ratio of 1.56:1. Mean NLR of patients treated surgically was raised (8.5±5.6) compared to conservatively treated patient (4.34). This value has sensitivity of 91% and specificity of 89% with Area Under Curve (AUC) of 0.941 with 95%confidence interval 0.895 to 0.987 and p value of<0.005.

Background: Acute appendicitis (AA) is one of the most common abdominal emergencies worldwide. Patients presenting with appendicitis may vary in severity. We conducted this study aiming top prospectively examine the role of NLR in assessing the severity of appendicitis, length of hospital stay, and rate of postoperative complications. We have 3 objectives namely to study neutrophil and lymphocyte count in appendicitis cases, to study various correlation and association regarding severity of appendicitis and neutrophil to lymphocyte ratio (NLR) & to study the validity of neutrophil to lymphocyte ratio (NLR) in predicting the severity, length of hospital stay and 30 day complication rate. The study was conducted in the department of general surgery at SAMC & PGI Indore (M.P.) from January 2018 to June 2019 on 100 patients which were selected according to inclusion and exclusion criteria Receiver Operating Characteristic (ROC) curve analysis was used for determining optimal cut-off value of NLR for complicated AA. Most of the patients with AA were in the age group of 20-29years with M:F ratio of 1.56:1. Mean NLR of patients treated surgically was raised (8.5±5.6) compared to conservatively treated patient (4.34). This value has sensitivity of 91% and specificity of 89% with Area Under Curve (AUC) of 0.941 with 95%confidence interval 0.895 to 0.987 and p value of<0.005.

Keywords

Acute appendicitis (AA), Neutrophil to lymphocyte ratio(NLR).

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
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