Background & Methods: the aim of the study is to establish imprint cytology technique as a routine procedure for intra-operative assessment of margin status in Carcinoma Breast Cases. Detailed clinical history and thorough physical examination were done in each patient. Complete pre-operative work-up investigations and medical fitness for surgery were obtained. Each patient was informed about the procedure and informed consent was obtained. Primary diagnoses were obtained by fine-needle aspiration cytology, stereotactic core biopsy, or other open biopsy procedures. Results: Plan for all our cases to start, was BCT with Axillary Sampling. Further course was based on Intra-op Imprint Cytology reported by pathologist. Imprint quoted free margins for 60 lumps out of which NO further dissection was done in 52 cases and surgery was completed after finishing Axillary Sampling. Inspite of negative Imprint, 08 cases were converted to MRM because of patient’s preference towards it. Involved margins were reported in 26 cases, out of which 24 were converted to MRM. For single case, patient refused MRM, hence margins were extended further 2 cm. Conclusion: Effective breast-conserving surgical techniques for early-stage disease were developed to improve breast cancer women’s quality of life. BCT may offer an advantage over MT in terms of body image, psychological and social adjustment, but BCT may be associated with higher rates of positive margins than MT and the incidence of local failure. Imprint cytology although not a substitute for conventional histopathology, but as complementary to it, is useful for rapid diagnosis of malignant conditions as well as benign conditions.

Background & Methods: the aim of the study is to establish imprint cytology technique as a routine procedure for intra-operative assessment of margin status in Carcinoma Breast Cases. Detailed clinical history and thorough physical examination were done in each patient. Complete pre-operative work-up investigations and medical fitness for surgery were obtained. Each patient was informed about the procedure and informed consent was obtained. Primary diagnoses were obtained by fine-needle aspiration cytology, stereotactic core biopsy, or other open biopsy procedures. Results: Plan for all our cases to start, was BCT with Axillary Sampling. Further course was based on Intra-op Imprint Cytology reported by pathologist. Imprint quoted free margins for 60 lumps out of which NO further dissection was done in 52 cases and surgery was completed after finishing Axillary Sampling. Inspite of negative Imprint, 08 cases were converted to MRM because of patient’s preference towards it. Involved margins were reported in 26 cases, out of which 24 were converted to MRM. For single case, patient refused MRM, hence margins were extended further 2 cm. Conclusion: Effective breast-conserving surgical techniques for early-stage disease were developed to improve breast cancer women’s quality of life. BCT may offer an advantage over MT in terms of body image, psychological and social adjustment, but BCT may be associated with higher rates of positive margins than MT and the incidence of local failure. Imprint cytology although not a substitute for conventional histopathology, but as complementary to it, is useful for rapid diagnosis of malignant conditions as well as benign conditions.