Background: Numerous functions have been made possible by notable advancements in dual-energy X-ray absorptiometry (DXA) in terms of quality, picture resolution, and acquisition time. By indirectly analyzing the micro- and macroarchitecture of the bone, DXA can assess bone quality and enhance fracture risk prediction. Additionally, without the need for additional radiologic imaging or radiation exposure, DXA can identify pre-existing fractures, such as atypical femur fractures or vertebral fractures. Furthermore, it can evaluate the metabolic state by the assessment of metrics related to body composition, such as visceral fat and muscle mass. DXA is obviously useful for more than simply bone mineral densitometry, even though additional research is needed to evaluate and apply these characteristics in a clinical setting. Aim of this study to correlate bone density DUAL ENERGY X-RAY ABSORPTIOMETRY in patient with femur fracture with markers of bone metabolism. Methods: This cross-sectional analytic study was conducted at Department of Orthopaedics, AIIMS, Raipur from 24 months after obtaining ethical clearance approval, sample collection – 12 months (April 2021 to March 2022), follow up – 6 months and article writing – 6 months. Total 99 patients were enrolled in this study. Results: This study by the Department of Orthopaedics, Raipur, correlated bone metabolism markers with dual energy X-ray absorptiometry in femur fracture patients (i.e. Serum calcium; Serum phosphorus; Alkaline phosphatase; Serum Vitamin D; and Serum protein – albumin). In this study of femur fractures, 99 cases met inclusion and exclusion criteria. The mean age of the population in our study was 51.44 ± 20.44 years with range (18-97 years). The majority of population the study group was male (65.7%) as compared to females (34.3%) in our study. Majority of the population had osteoporosis (47.3%) as compared to osteopenia in 31.3% of the population and normal bone mineral density in 21.2 % population. Mode of Injury reveals that Self fall (46.5%) and RTA (44.4%) were the most common mode of injury followed by fall from height (9.1%). Intertrochanteric femur fracture (42.4%) was the most common diagnosis followed by neck of femur fracture (28.3%) shaft of femur fracture (15.2%), distal femur fracture (9.1%) and subtrochanteric femur fracture (5.1%). ANOVA showed no significant association between bone mineral density and fracture groups (p value = 0.194) nor with the DXA parameters (T-score and Z-score; p value = 0.126, 0.092 respectively). Conclusion: We found a strong correlation between advanced age and low bone mineral density, even though blood calcium, serum vitamin D, and serum phosphorus have no effect on bone density. Bone mineral density is linked to blood alkaline phosphatase, serum albumin, and fracture prediction T- and Z-scores.

Background: Numerous functions have been made possible by notable advancements in dual-energy X-ray absorptiometry (DXA) in terms of quality, picture resolution, and acquisition time. By indirectly analyzing the micro- and macroarchitecture of the bone, DXA can assess bone quality and enhance fracture risk prediction. Additionally, without the need for additional radiologic imaging or radiation exposure, DXA can identify pre-existing fractures, such as atypical femur fractures or vertebral fractures. Furthermore, it can evaluate the metabolic state by the assessment of metrics related to body composition, such as visceral fat and muscle mass. DXA is obviously useful for more than simply bone mineral densitometry, even though additional research is needed to evaluate and apply these characteristics in a clinical setting. Aim of this study to correlate bone density DUAL ENERGY X-RAY ABSORPTIOMETRY in patient with femur fracture with markers of bone metabolism. Methods: This cross-sectional analytic study was conducted at Department of Orthopaedics, AIIMS, Raipur from 24 months after obtaining ethical clearance approval, sample collection – 12 months (April 2021 to March 2022), follow up – 6 months and article writing – 6 months. Total 99 patients were enrolled in this study. Results: This study by the Department of Orthopaedics, Raipur, correlated bone metabolism markers with dual energy X-ray absorptiometry in femur fracture patients (i.e. Serum calcium; Serum phosphorus; Alkaline phosphatase; Serum Vitamin D; and Serum protein – albumin). In this study of femur fractures, 99 cases met inclusion and exclusion criteria. The mean age of the population in our study was 51.44 ± 20.44 years with range (18-97 years). The majority of population the study group was male (65.7%) as compared to females (34.3%) in our study. Majority of the population had osteoporosis (47.3%) as compared to osteopenia in 31.3% of the population and normal bone mineral density in 21.2 % population. Mode of Injury reveals that Self fall (46.5%) and RTA (44.4%) were the most common mode of injury followed by fall from height (9.1%). Intertrochanteric femur fracture (42.4%) was the most common diagnosis followed by neck of femur fracture (28.3%) shaft of femur fracture (15.2%), distal femur fracture (9.1%) and subtrochanteric femur fracture (5.1%). ANOVA showed no significant association between bone mineral density and fracture groups (p value = 0.194) nor with the DXA parameters (T-score and Z-score; p value = 0.126, 0.092 respectively). Conclusion: We found a strong correlation between advanced age and low bone mineral density, even though blood calcium, serum vitamin D, and serum phosphorus have no effect on bone density. Bone mineral density is linked to blood alkaline phosphatase, serum albumin, and fracture prediction T- and Z-scores.