Background: Hospitals play a vital role in delivering healthcare services to the community, yet they encounter challenges affecting employee productivity, notably presenteeism—when employees are physically present at work despite health issues. Objectives: The research aims to look at the factors that influence the formation of presenteeism in hospital medical personnel Methods: The use of the structural equation model method was applied in this research using all nursing staff as the analysis unit at the National Brain Hospital. Prof. Dr. Mahar Mardjono, Jakarta Indonesia. Data collection used a survey compiled from indicators of the variables studied Results: From the results of data processing, it was found that presenteeism is influenced by employee job satisfaction, affective commitment, and organizational support both directly and indirectly. Even organizational support mediates the relationship between job satisfaction and presenteeism. These results indicate that presenteeism can be formed from three research variables, namely employee satisfaction, affective commitment and organizational support Implications: Research findings can be used by hospital management as an instrument for formulating strategies to develop presenteeism that has a positive impact and reduce the negative impact of the presence of presenteeism among hospital medical personnel.