Background: Closed isolated femur shaft fracture usually results from high energy trauma and traditionally assumed to have potential to cause hypotension that we rarely see in clinical practice. We wanted to find literature evidence of association between isolated closed femur shaft fracture and hypotension. Methods: Literature was searched on PubMed, Ovid databases and google scholar website. Hand-searching from references of the articles obtained. All the articles addressing this issue dating from 1955 to 2023 were included in this systematic review. Results: Overall, 13 articles were found that are directly or indirectly concerned about association of femur shaft fracture and hypotension. Out of which, 6 articles are directly related to isolated femur shaft fractures sustained in children or adults. 2 studies indirectly estimated high blood loss pattern with femur shaft fracture, but 5 studies that directly studied hypotension with isolated femur fractures in more than 500 patients, P values of these studies suggest isolated femur shaft fractures don’t cause hypotension. Conclusion: The available evidence from the studies that actually studied incidence of clinical hypotension in isolated femur shaft fractures show closed isolated femur shaft fractures rarely cause clinical hypotension.

Background: Closed isolated femur shaft fracture usually results from high energy trauma and traditionally assumed to have potential to cause hypotension that we rarely see in clinical practice. We wanted to find literature evidence of association between isolated closed femur shaft fracture and hypotension. Methods: Literature was searched on PubMed, Ovid databases and google scholar website. Hand-searching from references of the articles obtained. All the articles addressing this issue dating from 1955 to 2023 were included in this systematic review. Results: Overall, 13 articles were found that are directly or indirectly concerned about association of femur shaft fracture and hypotension. Out of which, 6 articles are directly related to isolated femur shaft fractures sustained in children or adults. 2 studies indirectly estimated high blood loss pattern with femur shaft fracture, but 5 studies that directly studied hypotension with isolated femur fractures in more than 500 patients, P values of these studies suggest isolated femur shaft fractures don’t cause hypotension. Conclusion: The available evidence from the studies that actually studied incidence of clinical hypotension in isolated femur shaft fractures show closed isolated femur shaft fractures rarely cause clinical hypotension.