Klebsiella associated infections is the emergence of multi-drug resistant strains particularly those involved in nosocomial diseases. Hence, this study has been designed to determine the isolation rate of Klebsiella pneumoniae, their antibiogram in various clinical samples in patients admitted in intensive care units of a tertiary care hospital. A total of 6274 clinical samples were processed during the study period. Out of which 185 (2.94%) Klebsiella pneumoniae isolates were identified from various clinical samples during the study period. It was isolated highest in ET secretion samples (9.73%), followed by urine (2.18%), pus (1.34%) and blood (1.02%). Imipenem (58%) & Meropenem (58%) showed highest sensitivity followed by Amikacin (52%), Gentamicin (35%). Susceptibility to 3rd generation cephalosporins and beta-lactum & betalactamase inhibitor combinations was 10%-20%. We noticed that Klebsiella pneumoniae resistant to a wider range of antibiotics. Both morbidity and mortality is increased when infection is caused by these drug resistant organisms.

Klebsiella associated infections is the emergence of multi-drug resistant strains particularly those involved in nosocomial diseases. Hence, this study has been designed to determine the isolation rate of Klebsiella pneumoniae, their antibiogram in various clinical samples in patients admitted in intensive care units of a tertiary care hospital. A total of 6274 clinical samples were processed during the study period. Out of which 185 (2.94%) Klebsiella pneumoniae isolates were identified from various clinical samples during the study period. It was isolated highest in ET secretion samples (9.73%), followed by urine (2.18%), pus (1.34%) and blood (1.02%). Imipenem (58%) & Meropenem (58%) showed highest sensitivity followed by Amikacin (52%), Gentamicin (35%). Susceptibility to 3rd generation cephalosporins and beta-lactum & betalactamase inhibitor combinations was 10%-20%. We noticed that Klebsiella pneumoniae resistant to a wider range of antibiotics. Both morbidity and mortality is increased when infection is caused by these drug resistant organisms.