Knee joint osteoarthritis (OA) is a common disease which causes seriousjoint inflammation and strictly limits patients’ usual mobility. Indeed a significantproportion of diabetic patients are victims of this knee joint OA. Concerning theeffect of knee OA, present study was carried out, (i) to assess the proportion ofosteoarthritis of knee joint among diabetic patients; and (ii) to investigate the effectof various risk factors (e.g. blood glucose level, duration of diabetes, effect ofexercise) which are strictly associated with osteoarthritis. 150 diabetic patients(33.3% male and 60.7% female) of mid age were enrolled for this purpose. It hasrevealed from the present investigation that out of 150 diabetic patients 74% hadosteoarthritis. On the other hand depending on the associated risk factors,percentage of knee joint osteoarthritis varies among the respondents. Nevertheless,it has been concluded from the present study that osteoarthritis is a distressingproblem in people suffering from type 2 diabetes mellitus.