Almost all parts of medicinal plant Cydonia oblonga Mill., known as “Quince” belonging to Rosaceae family, such as seeds, buds, leaves, fruit and peel are used to prevent or treat several ailments such as cancer, diabetes, hepatitis, ulcer, respiratory, and urinary infections, etc. It is rich in useful secondary metabolites such as phenolics, pectin, steroids, flavonoids, terpenoids, tannins, sugars, organic acids, glycosides and essential oils with a wide range of pharmacological activities like cardiovascular, hypoglycemic, nephro, hepato and UV-protective, aphrodisiac, antioxidant, anti-allergic, anti-atherosclerotic, antimicrobial, antibacterial, antifungal, antihypertensive, hypolipidemic, diuretic, antidiarrheal, antidepressant, antispasmodic, and anti-inflammatory effects. It is used as a single drug or as an ingredient in various formulations such as syrup, extract, confection, semisolid preparations and pill. This review focuses on detailed investigations of pharmacological and phytomedicinal attributes of the plant, from past to present, which are reported in Books and Scientific Journals. Keywords: Quince, Cydonia oblonga, Herbal Medicine, Pharmacological Effects.