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ZENODO
Article . 2024
License: CC BY
Data sources: ZENODO
ZENODO
Article . 2024
License: CC BY
Data sources: Datacite
ZENODO
Article . 2024
License: CC BY
Data sources: Datacite
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A Hospital Based Observational Study to Assess the Association of Dengue Serology with Variations in RBC Parameters

Authors: Manish Kumar Jha; Poonam Kumari; Madhu Bharti;

A Hospital Based Observational Study to Assess the Association of Dengue Serology with Variations in RBC Parameters

Abstract

Aim: The aim of the present study was to assess the association of dengue serology with variations in RBCparameters.Methods: The present study was conducted in the Department of Pathology. Out of 200 total study populations,100 were dengue positive and 100 were dengue negative.Results: Multiple logistic regression showed thrombocytopenia, leukopenia (ORA = 0.999; p < 0.001), glucoselevel, aspartate aminotransferase and monocytosis as significant parameters in the NS1-only positive group.Similarly, thrombocytopenia, glucose level and aspartate aminotransferase were significant in IgM-only positivepatients. Moreover, thrombocytopenia, leukopenia, glucose, aspartate aminotransferase and lymphopenia wereindependent predictors in both NS1 + IgM positive groups.Conclusion: The study found that certain hematological and biochemical parameters can predict the outcome ofdengue infection, which can assist physicians in the diagnosis and proper patient management. Parameters, suchas thrombocytopenia, AST, hyperglycemia, and leukopenia with monocytosis (in the NS1-only phase);thrombocytopenia, elevated AST, and high blood glucose (in the IgM-only phase); and thrombocytopenia,elevated AST, high blood glucose, and leukopenia with lymphopenia (in the dual-positive/both NS1 + IgM phase),can provide insight into dengue positivity and help with patient management.

Aim: The aim of the present study was to assess the association of dengue serology with variations in RBCparameters.Methods: The present study was conducted in the Department of Pathology. Out of 200 total study populations,100 were dengue positive and 100 were dengue negative.Results: Multiple logistic regression showed thrombocytopenia, leukopenia (ORA = 0.999; p < 0.001), glucoselevel, aspartate aminotransferase and monocytosis as significant parameters in the NS1-only positive group.Similarly, thrombocytopenia, glucose level and aspartate aminotransferase were significant in IgM-only positivepatients. Moreover, thrombocytopenia, leukopenia, glucose, aspartate aminotransferase and lymphopenia wereindependent predictors in both NS1 + IgM positive groups.Conclusion: The study found that certain hematological and biochemical parameters can predict the outcome ofdengue infection, which can assist physicians in the diagnosis and proper patient management. Parameters, suchas thrombocytopenia, AST, hyperglycemia, and leukopenia with monocytosis (in the NS1-only phase);thrombocytopenia, elevated AST, and high blood glucose (in the IgM-only phase); and thrombocytopenia,elevated AST, high blood glucose, and leukopenia with lymphopenia (in the dual-positive/both NS1 + IgM phase),can provide insight into dengue positivity and help with patient management.

Keywords

dengue serology, RBC parameters

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
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