
Alcohol consumption has been steadily increasing all over world, especially in India. Alcohol can cause physical, mental and social effects which is determined by quantity and pattern of alcohol drinking. All organs can be damaged due to direct effects of alcohol, especially the digestive and nervous systems. At the level of digestive system, alcohol causes gastrointestinal problems, cirrhosis of liver, pancreatitis and cancer of mouth, pharynx and oesophagus. The present study aims to compare the values of Liver function test, LFT parameters in a group of chronic alcoholics and a matched controlled group (non-alcoholics). SGOT levels were more in alcoholic subjects as compared to control subjects and this difference was statistically highly significant. SGPT levels were significantly higher in alcoholic subjects as compared to control group subjects. Total bilirubin direct bilirubin, was more in alcoholic subjects as compared to control subjects and this difference was statistically highly significant. Total protein, albumin was low in alcoholic subjects as compared to control subjects. The present study clearly establishes that alcohol has direct effect on the physiological functioning of the liver which is proved by alteration in liver function tests.
Alcohol consumption has been steadily increasing all over world, especially in India. Alcohol can cause physical, mental and social effects which is determined by quantity and pattern of alcohol drinking. All organs can be damaged due to direct effects of alcohol, especially the digestive and nervous systems. At the level of digestive system, alcohol causes gastrointestinal problems, cirrhosis of liver, pancreatitis and cancer of mouth, pharynx and oesophagus. The present study aims to compare the values of Liver function test, LFT parameters in a group of chronic alcoholics and a matched controlled group (non-alcoholics). SGOT levels were more in alcoholic subjects as compared to control subjects and this difference was statistically highly significant. SGPT levels were significantly higher in alcoholic subjects as compared to control group subjects. Total bilirubin direct bilirubin, was more in alcoholic subjects as compared to control subjects and this difference was statistically highly significant. Total protein, albumin was low in alcoholic subjects as compared to control subjects. The present study clearly establishes that alcohol has direct effect on the physiological functioning of the liver which is proved by alteration in liver function tests.
Liver Function Test, Alcoholics
Liver Function Test, Alcoholics
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