Background: A complex combination of diffuse parenchymal lung conditions, interstitial lung disease is characterized by restrictive physiology, decreased gas perfusion, inflammation of the lung parenchyma, and fibrosis. The pulmonary interstitium, which is made up of the connective tissue space between the alveolar epithelial cells and the nearby capillary endothelial cells, is primarily responsible for the pathophysiology of interstitial lung disease. Methods: The study was conducted from July 2022 to December 2022 in the department of Respiratory Medicine at Varun Arjun Medical College, Banthra, and Shahjahanpur. Total 60 patients, 36 male and 24 female included in this study. The male female ratio 1.5:1. Results: Exertional dyapoea was the most common presenting symptom; second most common symptom was nonproductive cough. COPD was the commonest comorbid illness, second commonest comorbid condition absorbed was mellitus. Out of the 36 men, 25 were Smokers (42%) of the 19 Patients with IPF 16 were smokers. Average smoking index was found to be 180. 21.58% patients had upper zone predominance in chest x- ray. 4 out of 60 patients had mid zone perihilar distribution of lesion. 29 out of 60 patients had lower zone predominance. Spirometry showed restrictive in 86 % of Patients. Conclusion: The profile of ILDs with their demographic, clinical and outcome data were analyzed and compared with other regional and global studies. The results recognized certain similarities and differences compared to other reports, formulating a distinctive study among others. Idiopathic interstitial pneumonias were the commonest type of ILD in studied sample, followed closely by secondary ILDs.

Background: A complex combination of diffuse parenchymal lung conditions, interstitial lung disease is characterized by restrictive physiology, decreased gas perfusion, inflammation of the lung parenchyma, and fibrosis. The pulmonary interstitium, which is made up of the connective tissue space between the alveolar epithelial cells and the nearby capillary endothelial cells, is primarily responsible for the pathophysiology of interstitial lung disease. Methods: The study was conducted from July 2022 to December 2022 in the department of Respiratory Medicine at Varun Arjun Medical College, Banthra, and Shahjahanpur. Total 60 patients, 36 male and 24 female included in this study. The male female ratio 1.5:1. Results: Exertional dyapoea was the most common presenting symptom; second most common symptom was nonproductive cough. COPD was the commonest comorbid illness, second commonest comorbid condition absorbed was mellitus. Out of the 36 men, 25 were Smokers (42%) of the 19 Patients with IPF 16 were smokers. Average smoking index was found to be 180. 21.58% patients had upper zone predominance in chest x- ray. 4 out of 60 patients had mid zone perihilar distribution of lesion. 29 out of 60 patients had lower zone predominance. Spirometry showed restrictive in 86 % of Patients. Conclusion: The profile of ILDs with their demographic, clinical and outcome data were analyzed and compared with other regional and global studies. The results recognized certain similarities and differences compared to other reports, formulating a distinctive study among others. Idiopathic interstitial pneumonias were the commonest type of ILD in studied sample, followed closely by secondary ILDs.