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ZENODO
Dataset . 2017
License: CC BY NC
Data sources: Datacite
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ZENODO
Dataset . 2017
License: CC BY NC
Data sources: ZENODO
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ZENODO
Dataset . 2017
License: CC BY NC
Data sources: Datacite
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Recolector de Ciencia Abierta, RECOLECTA
Dataset . 2021 . Peer-reviewed
Data sources: Recolector de Ciencia Abierta, RECOLECTA
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Recolector de Ciencia Abierta, RECOLECTA
Dataset . 2017 . Peer-reviewed
Data sources: Recolector de Ciencia Abierta, RECOLECTA
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DIGITAL.CSIC
Dataset . 2021 . Peer-reviewed
Data sources: DIGITAL.CSIC
DIGITAL.CSIC
Dataset . 2017
License: CC BY NC
Data sources: Datacite
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Claim

Epigenome-wide analysis reveals specific DNA hypermethylation of T cells during human hematopoietic differentiation

Research datakeyboard_double_arrow_right Dataset 01 Jan 2017Embargo end date: 17 Mar 2021 Spain English Publisher:ZenodoFunded by:EC | INFANTLEUKEMIA
Authors: Tejedor, J Ramon; Bueno, Clara; Cobo, Isabel; Bayon, Gustavo F; Prieto, Cristina; Mangas, Cristina; Pérez, Raul F.; +5 Authors

doi: 10.20350/digitalcsic/13819 , 10.5281/zenodo.1095572 , 10.5281/zenodo.1095571

handle: 10261/235141

Epigenome-wide analysis reveals specific DNA hypermethylation of T cells during human hematopoietic differentiation

Abstract

Epigenetic regulation plays an important role in cellular development and differentiation. A detailed map of the DNA methylation dynamics that occur during cell differentiation would contribute to decipher the molecular networks governing cell fate commitment. In this study we used the most recent Illumina MethylationEPIC Beadchip platform to describe the genome-wide DNA methylation changes observed throughout hematopoietic maturation by analyzing multiple hematopoietic cell types at different developmental stages.

Supplementary figures and supplementary data tables from MethylationEPIC arrays (Tejedor et al), plus a compiled dataset including raw methylation intensities, processed β-values and Phenotypic data from HumanMethylation450 arrays collected from datasets GSE63409, GSE49618, GSE88824 and GSE49031, and HumanMethylationEPIC arrays deposited in E-MTAB-6315 entry from ArrayExpress.

Grants: European Commission: INFANTLEUKEMIA - GENOMIC, CELLULAR AND DEVELOPMENTAL RECONSTRUCTION OFINFANT MLL-AF4+ ACUTE LYMPHOBLASTIC LEUKEMIA (646903).

Peer reviewed

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Spain
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Keywords

Hematopoietic differentiation, DNA methylation, MethylationEPIC beadchip, T lymphocytes, DNA enhancers.

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
views
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