IMMUNOPATHOGENESIS OF DENGUE DISEASE (DENV)

There iis ia lot iof iresearch ion ithe ivaried ievolution iof idengue ivirus i(DENV) iinfection in humans. Dengue ishock isyndrome (DSS), idengue ihemorrhagic ifever i(DHF), and animal models, and human data since DENV's icellular iand itissue itropism are thought ito be isignificant idengue iillness ifactors. Dengue ivirus iresearch ispanning moreithan i50 years ihas iyielded ia substantial idataset idemonstrating ithe irelationship between ivirulence variables iand idetrimental ihost iresponses iand ithe defectiveihemostasis and iincreased vascular ipermeability icaused iby DHF and DSS istrains. iDSS's underlying ivascular hyperpermeability imay ibe ifacilitated iby itargeted idifferentiation iof particular ivascular beds. iA ipersonalized iapproach ito i development iresearch iwill ireveal the ibasis iof individual irisk ifor ithe idevelopment iof iDHF iand iDSS iand iidentify i genetic and environmental ifactors ifor idistinct irisk ifactors ifor ithe idevelopment iof serious idisease.

Related Organizations

Sharda University
India

Keywords

Dengue Virus; Exosomes; Host Immune Response; Immunopathogenesis; Inflammation.

Impact byBIP!

	selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	0
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average