This document provides the description of the work carried out to design and implement strategies for thegeneration of synthetic data that can be used as demonstrators of the technical developments within andbeyond the project. The generated synthetic data can be freely available, hence it can be shared among allpartners without the need of data transfer or sharing agreements. Cancer specific synthetic cohorts includingdifferent modalities (i.e., genomic data together with clinical data based on OMOP) will be created, delivered,and stored in publicly available repositories (e.g., EGA).