The present document is a pdf version of the CENTRINNO Framework, updated during the project's life. CENTRINNO is a research project that aims at demonstrating how industrial historic sites could adopt innovative, sustainable and inclusive urban transformation processes. The CENTRINNO Framework attempts at creating a common language for all the project partners to understand each other and share our findings with a wider research audience, being able to explain what, why and how things are done in CENTRINNO. This GitBook is a living document where the different pieces of the project come together, building on the fly this common language and reporting and sharing it during the project's life. This document target audience are CENTRINNO pilot cities and project partners, but also policymakers, local governments, or researchers who are interested in following and applying the CENTRINNO approach, methods, and tools in other cities. Based on Fab City's approach towards resilient and productive cities and regions, CENTRINNO supports experimentation in nine European cities to transform historic industrial sites into productive and creative hubs. The project started in September 2020 and last until February 2024. This present gitbook has been updated and iterated, based on CENTRINNO's experience.