This study aimed to identify the challenges of municipal solid waste management in Itam, Uyo and to proffersolutions to addressing them. The study identified inadequate public waste disposal bins in the area study evenas the populace refered dumping their waste in public disposal units for it to be collected the responsible wastemanagement agency. The ineffective collection of waste at collection points occasioned indiscriminate dumpingof waste. To addressing these challenges, this paper presented a strategy of improving waste managementprocess by utilizing Artificial Intelligent ‘AI’ to optimizing waste collection routing of garbage trucks forefficient tracking and monitoring of waste management facilities, estimating the waste generation patterns at thewaste collection points and for efficient planning and allocation of MSW management resources. IncorporatingAI in the municipal solid waste management system enhances its operational guidelines and efficiency.