Background: This case report explores the use of homeopathic sarcodes in managing hypothyroidism, an endocrine disorder. The study found that homoeopathic medicines correct metabolism without adverse effects. A 15-year- old female with hypothyroidism was prescribed thyroidinum 6x two times a day for a month, resulting in normal parameters.  Objectives: Study the effectiveness of homeopathic sarcodes in managing hypothyroidism and their role in treating Endocrine Disorders.  Methods: A case report that examined the effectiveness of homoeopathic treatment in treating endocrine diseases i.e. hypothyroid, by searching the PubMed and Google Scholar databases. Following abstract assessment, the full texts of the articles that made the shortlist were examined for study design.  Results: Summary of the case: A 15-year-old female with hypothyroidism 11.61 uIU/mL with complaints of weight gain, dry skin, fatigue, and hair loss. was treated with thyroidinum 6x tablets for a month, demonstrating the efficacy of homoeopathic treatment. The isopathic use of auto-sarcode of DNA could potentially treat chronic disorders, The study utilized Google Scholar and PubMed databases to identify studies on statistics, homeopathic immunity, and homoeopathic sarcodes, clinical studies, revealing that homoeopathic medicines effectively treat conditions without adverse effects but rigorous research and clinical trials are needed.  Conclusion: Endocrine disorders affect various aspects of life, including physical, psychological, and financial well- being. Homoeopathy strengthens the immune system using pharmaceuticals, while organotherapy uses animal health tissues to treat patients. Both methods follow Homeopathy principles, focusing on the same cures. Organotherapy uses identical organ extracts and activity by potency to strengthen organs and tissues weakened by toxins, while low potency stimulates underactive organs or tissues. Keywords:- Homoeopathy, Endocrine Disorders, Immunity In Homoeopathy.