Since the advent of glucocorticoid therapy for autoimmune diseases in 1940s, their widespread application has led to the concurrent therapy limiting discovery of many adverse metabolic side effects. Steroid is a biologically active organic compound having immunosuppressive action in living organisms. It can cause a deviation in the blood glucose level of patient. Unanticipated hyper glycemia associated with the initiation of glucocorticoids often leads to prolonged hospital stays, increased risks for infection etc. Glucocorticoids are extensively used in every areas of medicine. Although it is widely prescribed for their anti-inflammatory and immunosuppressive properties. Recently Steroid Induced Diabetes Mellitus (SIDM) has been recognized as severe and important side effect. SIDM is defined as an abnormal increase in blood glucose associated with the use of glucocorticoids in a patient with or without a prior history of Diabetes Mellitus. It is a typical case on steroid induced diabetic intolerance. Keywords: Diabetes Mellitus, Diabetic intolerance, Steroids