Nanoparticles(NPs) are solid,spherical particles of size 100nm,prepared from polymers(natural or synthetic).Hydrophobic and hydrophoilic drugs,vaccines and macromolecules can be delivered by using NPs,which may also allow controlled drug delivery or a targeted administration to a specific cell or organ. Nanotechnology is an emerging scientific discipline with numerous applications in the field of biomedicine and manufacturing new materials.Plenty and pretty applications of nanoparticles have gained utmost priority now-a-days due to their versatile flexibility in wide range of applications.Some nanoparticles also show bactericidal effects and hence a high surface to volme ratio. Due to their unique properties, small size and high area to volume ratio ,gold nanoparticles.Show special advantages in this field among nanoparticles ,biosynthesized gold NPs remarkable applications in different and chemicals sensors ,heavy metals ion detection,electrical coatings.During the last two decades ,NPs have been extensively investigated and developed in imaging applications due to the superior narrow range of emission,photo stability,broad excitation wavelength,quantum dots have attracted the attention from scientists and engineers interested in drug targeting,biomarkers and sensors. Keywords: Gold nanoparticles, Nanotechnology, drug delivery, biomedical applications.