The gingival fluid of pregnant women was studied for interleukins 8 and 10, and immunoglobulins A and G in 31 female patients of SHI CH No.5 of Volgograd, at the age of 20-25 years - the first period of adulthood (Iordanishvili A.K., 2015), 15 of which - without IDA, and 16 - with manifestations of IDA. Treatment of mild and moderate periodontitis (K05.3) was carried out in pregnant women with IDA with the use of Lysobact; pregnant women without IDA were treated with traditional anti-inflammatory therapy according to the treatment algorithm. In both groups, professional oral hygiene, active training and monitoring of the performance of individual hygiene were carried out. It was established that the concentration of IL-10 increases significantly (p <0.05) from 0.010 [1.790] ng/ml to 3.050 [8.550] ng/ml after treatment, against the background of complex treatment of periodontitis in pregnant women with IDA with Lysobact. This confirms the importance of interleukin 10 as the main anti-inflammatory cytokine and objectively proves the correctness of the selected clinical tactics for treating mild and moderate inflammatory periodontal diseases with the drug "Lysobact" against the background of iron deficiency anemia. Keywords: pregnant women, iron deficiency anemia, periodontal disease.