The study sought to investigate the effect of business re-engineering on the performance of Equity bank, Kenya and the corresponding hypothesis was formulated and tested. The study targeted 63 employees of the Equity bank and 62 of them responded. The study adopted a descriptive research design and positivist research philosophy. SPSS version 26 was used to analyze data using correlation and regression analysis. Research findings from the test of hypothesis established that business re-engineering had a positive and significant effect on bank performance. The study findings support Resource Based View Theory, Diffusion of Innovation Theory and Technology Acceptance Model (TAM).