Hypoglycemia is a condition caused by very low level of sugar (glucose) which is the main energy source of the body. Hypoglycemia is often related to treatment of diabetes. However, a variety of conditions may cause low blood sugar level in people without diabetes like fever, Hypoglycemia is not a disease itself, it’s an indicator of health problem. A survey on incidence and severity of hypoglycemia in a tertiary care Centre with administration of a questionnaire a prospective study was conducted in Apollo Hospitals, Jubilee Hills, Hyderabad. Outpatients enrolled in the study were fully informed and gave their consent. Information was gathered regarding patient demographics, location, risk factors, co-morbid conditions, treatment, ADR, episodes of hypoglycemia. A total of 270 patients were enrolled for the study among which 55% were males and 45% were females. Hypoglycemia was seen in (6%) of the study population. The study results suggested that hypoglycemic incidence was higher in the age groups of 42-67 years (38%). Co-morbid conditions were seen in (52.9%) of the study population which included, HTN, CKD, Thyroid (6.7%), and renal failure (3.3%). The study concludes that the most common reasons of hypoglycemia were altered food habits and the drugs. Sulphonylureas are the drugs involved majorly in the hypoglycemic episodes. Key words: Hypoglycaemia, Incidence, Tertiary care