Work Package 4 of the AFFIRMO project conducts a mixed-methods study to understand the needs of patients, caregivers, and healthcare professionals in managing multimorbidity, including atrial fibrillation (AF). The goal is to develop a patient-centered approach for older multimorbid AF patients. This report focuses on the online survey results, which involved 1,305 participants and identified 53 items, including key needs, quality performance indicators, and outcomes. Sex differences impact patient engagement, with men generally more engaged and satisfied with care. Age, education, and the number of co-morbidities also influence engagement levels. Caregiver findings show age and education affecting quality of life, and country-specific differences. Engagement personas are defined based on characteristics and empowerment levels using different scales for patients and caregivers, highlighting varying aspects of the engagement process.