Introduction: The removal of the gall bladder is one of the most frequent procedures and is known as cholecystectomy. The typical cholecystectomy surgery uses an open method. Patients typically had a 2 to 6-day postoperative in-house stay, and this typically involved undergoing an intraoperative cholangiogram. A less invasive surgical procedure called laparoscopic cholecystectomy removes a diseased gallbladder. For cholecystectomies, this method essentially supplanted the open method. The management of cholecystitis, symptomatic cholelithiasis, biliary dyskinesia, acalculous cholecystitis, gallstone pancreatitis, and gallbladder tumors or polyps is currently indicated by laparoscopic cholecystectomy. In managing acute cholecystitis, laparoscopic cholecystectomy has gained popularity as an alternative to open cholecystectomy. The ideal management of symptomatic cholelithiasis and chronic cholecystitis is now laparoscopic cholecystectomy. Aim of the study: The purpose of this review is to understand the difference between open and laparoscopic cholecystectomy. Methodology: The review is the comprehensive research of PUBMED since the year 2013 to 2022. Conclusion: Regardless of the surgical approach employed, the indications that lead the surgeon to undertake a partial cholecystectomy are inherently vulnerable to problems. However, compared to an open treatment, a laparoscopic technique has benefits like a quicker recovery period and shorter hospital stay after surgery. It also has a lower risk of wound infection and incisional hernias. The surgical team should never hesitate to move to an open cholecystectomy, though, if they lack sufficient experience. Keywords: Gallbladder removal, Open cholecystectomy, Laparoscopic cholecystectomy, etc.