
Fig. 1. Hypothetical biosynthetic pathway of carnosic acid (4) and carnosol (5) produced in Rosmarinus officinalis. Based on the universal diterpenoid precursor geranylgeranyl diphosphate (GGDP) (1), the first steps of carnosic acid biosynthesis are proposed to proceed via a copalyl diphosphate intermediate (copalyl-DP) (2) provided by copalyl diphosphate synthase (CPS), and followed by the production of an abietane-like diterpene (3) catalyzed by a kaurene synthase-like enzyme (KSL).
Biodiversity, Taxonomy
Biodiversity, Taxonomy
