This study explores the application of various machine learning models to predict vehicle fuel consumption using the Auto MPG dataset. It examines the effectiveness of algorithms such as Decision Tree Regressors, Random Forests, Support Vector Regressors, and neural network-based models like LSTM and GRU. The study aims to enhance fuel efficiency prediction by analyzing factors like engine specifications, driving habits, and vehicle design. The models' performance is evaluated using metrics such as R-squared (R2), Root Mean Square Error(RMSE), Mean Absolute Error (MAE), and Mean Absolute Percentage Error (MAPE) to ensure accuracy and minimize error.