As an extension of an intuitionistic fuzzy set, a single-valued neutrosophic set is described independently by the membership functions of its truth, indeterminacy, and falsity, which is a subclass of a neutrosophic set (NS). However, in existing exponential operations and their aggregation methods for neutrosophic numbers (NNs) (basic elements in NSs), the exponents (weights) are positive real numbers in unit intervals under neutrosophic decision-making environments. As a supplement, this paper defines new exponential operations of single-valued NNs (basic elements in a single-valued NS), where positive real numbers are used as the bases, and single-valued NNs are used as the exponents. Then, we propose a single-valued neutrosophic weighted exponential aggregation (SVNWEA) operator based on the exponential operational laws of single-valued NNs and the SVNWEA operator-based decision-making method. Finally, an illustrative example shows the applicability and rationality of the presented method. A comparison with a traditional method demonstrates that the new decision-making method is more appropriate and effective.