This deliverable provides guidelines on how to implement the Virtual Laboratories (VLabs) in the Blue-Cloud Virtual Research Environment (VRE). First a summary of the activities of WP4 is presented, followed by an overview of the VRE services, that offer a comprehensive array of features, fostering collaboration, facilitating data analytics, enabling result dissemination, and ensuring seamless integration with external systems. In fact, the VRE caters to the entirety of the research lifecycle.