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The potential of graphene oxide surfaces to reduce biofilms formed by uropathogens

Research datakeyboard_double_arrow_right Dataset 12 Dec 2023 English Publisher:Zenodo

Authors: Belo, Samuel; Sousa-Cardoso, Francisca; Teixeira-Santos, Rita; Gomes, Luciana; Vieira, Rita; Sjollema, Jelmer; Soares, Olívia; +1 Authors

doi: 10.5281/zenodo.10367539 , 10.5281/zenodo.10367538

The potential of graphene oxide surfaces to reduce biofilms formed by uropathogens

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Abstract

Polydimethylsiloxane (PDMS), 5 wt.% GNP/PDMS (GNP/PDMS), 1 wt.% graphene oxide (GO)/PDMS (GO1/PDMS), 3 wt.% GO/PDMS (GO3/PDMS), 5 wt.% GO/PDMS (GO5/PDMS)) were analyzed regarding hydrophobicity and roughness. Staphylococcus aureus and Pseudomonas aeruginosa biofilms were developed on these different surfaces under static conditions for 24h at 37°C. The number of biofilm total and culturable cells was quantified by flow cytometry and plate counts, respectively, whereas the biofilm amount was determined by crystal violet staining. Moreover, the mechanisms of action of GO were characterized using the flow cytometer.

Related Organizations

University of Groningen
Netherlands
Universidade do Porto
Portugal
University Medical Center Groningen
Netherlands

Keywords

graphene oxide; urinary catheters

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