This review aimed to assess the stress. Stress is a fact in our daily life. when a person needs help, it means it means that persons feel that personally and emotionally disabled. Most people believe that their capacity and capabilities are so little to encounter the stress. If you experience stress over a prolonged period of time, it could become chronic, till you take some action. About 500 million people worldwide are believed to be suffering from, stress related and psychological problems. While everyone understands the symptoms of the stress response. Stress is mainly dependence on the neuroendocrine system. However, the stress effects on the immune system is disputed, and caused various "immunodeficiency linked” diseases. Using self help techniques like yoga, adult painting , dairy writhing to reduce the stress. Mainly this paper will present a discussion of stress: how stress is defined, biology, physiology and some examples are given how manage the stress.