Design: Observational study design. Background: Hypothyroidism is the clinical syndrome and associated with slowing down the metabolic process in the body. Thyroid function significantly affects lipoprotein metabolism as well as some cardiovascular disease. Objectives: To assess the correlation between of thyroid functions and lipid abnormalities. . Methods: 20 Hypothyroidism patients were selected through convenience random sampling for the study. Blood sample was withdrawn from patients of hypothyroidism after overnight fasting and used for biochemical analysis. Results: Results of the study revealed that there was a statistically significant positive correlation between serum TSH, LDL, statistically significant negative correlation between serum TSH, and HDL. Conclusion: Thyroid dysfunction can have an important effect on lipid profile. Therefore, patients presenting with dyslipidemia are recommended to be investigated for hypothyroidism.