techUK and Health Data Research UK (HDRUK) held a roundtable discussion on 1st November 2023 to explore the use of the Observational Medical Outcomes Partnership (OMOP) Common Data Model (CDM) in Secure Data Environments (SDEs) and elsewhere in the NHS and research. The panel included representatives from industry, NHS organisations and academic research. The OMOP Common Data Model has been widely adopted to support the generation of Real World Evidence from routinely collected health data. The use of a CDM permits studies to be conducted across multiple sites, organisations and countries. Importantly, OMOP has been adopted as a CDM by the Data for R&D Programme's NHS Research Secure Data Environment Network. The panel discussed the challenges and barriers to the adoption of OMOP, and suggested steps that could enable them to be overcome.