Great Ape Cerebral Aging - Expansion Relationship

This contains data associated with the manuscript "The Uniqueness of Human Vulnerability to Brain Aging in Great Ape Evolution" https://www.biorxiv.org/content/10.1101/2022.09.27.509685v1 The chimp.zip and IXI.zip contain data for the chimpanzee and human samples respectively. This includes the input matrix (subject x gray matter voxels), OPNMF bootstrap outputs, and OPNMF parcellaitons (2-40). The outputs.zip contains outputs from the analyses conducted for the manuscript using the code from https://github.com/viko18/GreatApe_Aging. The expansion_map.zip contains the modulated jacobians and templates following cross-species registration for the chimpanzee, baboon, and macaque templates. y_JunaChimp_brain.nii.gz is the deformtion field map from chimpanzee template space to human and iy_*.nii.gz is the inverse, so human to chimpanzee. Davi130_MNI_3mm_cortex.nii.gz is the avi130 chimpanzee parcellation in human MNI sapce.

Related Organizations

Forschungszentrum Jülich
Germany
Jena University Hospital
Germany
George Washington University
United States
Helmholtz Association of German Research Centres
Germany

Keywords

Aging, Chimpanzee, Great Apes, Evolution, MRI

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