A common plant in India is the herbaceous vine Tinospora cordifolia, sometimes known as the Giloy. The conventional Ayurvedic medical system makes extensive use of it. Plants have long been a rich source of medicines, dating back to the beginning of human civilization. This report discusses a survey of the component chemicals found in Tinospora cordifolia and their pharmacological properties. Immune suppression is a factor in the development of conditions such as obstructive jaundice, hepatic fibrosis, dyspepsia, urinary tract infections, fever, diabetes, anaemia, and inflammation. T. cordifolia has a wide range of chemicals that have cytotoxic and immunomodulatory properties, and they have been employed in traditional medical systems. This review aims to condense important information on chemical constituents, chemical structure, and pharmacokinetic activities such as anti-diabetic, anti-cancer, immune-modulatory, antivirus, antioxidant, antimicrobial, hepatoprotective, and their impact on cardiovascular and neurological disorders as well as rheumatoid arthritis. Key Words: -Tinospora cordifolia, Guduchi, Menispermaceae, Tinosporic acid.